Therapeutic Effects of Upadacitinib on Experimental Autoimmune Uveitis: Insights From Single-Cell Analysis

PURPOSE: This study aimed to elucidate the impact of upadacitinib, a Janus kinase 1 (JAK1)-specific inhibitor, on experimental autoimmune uveitis (EAU) and explore its underlying mechanisms. METHODS: We utilized single-cell RNA sequencing (scRNA-seq) and single-cell assay for transposase-accessible...

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Detalles Bibliográficos
Autores principales: Huang, Zhaohao, Jiang, Qi, Chen, Junjie, Liu, Xiuxing, Gu, Chenyang, Tao, Tianyu, Lv, Jianjie, Li, Zhaohuai, Li, Zuohong, Su, Wenru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Immunology and Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506681/
https://www.ncbi.nlm.nih.gov/pubmed/37713206
http://dx.doi.org/10.1167/iovs.64.12.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506681/
https://www.ncbi.nlm.nih.gov/pubmed/37713206
http://dx.doi.org/10.1167/iovs.64.12.28

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