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Prediction of hot spots towards drug discovery by protein sequence embedding with 1D convolutional neural network
Protein hotspot residues are key sites that mediate protein-protein interactions. Accurate identification of these residues is essential for understanding the mechanism from protein to function and for designing drug targets. Current research has mostly focused on using machine learning methods to p...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506709/ https://www.ncbi.nlm.nih.gov/pubmed/37721924 http://dx.doi.org/10.1371/journal.pone.0290899 |