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RapaCaspase-9-based suicide gene applied to the safety of IL-1RAP CAR-T cells

Even if adoptive cell transfer (ACT) has already shown great clinical efficiency in different types of disease, such as cancer, some adverse events consistently occur, and suicide genes are an interesting system to manage these events. Our team developed a new medical drug candidate, a chimeric anti...

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Detalles Bibliográficos
Autores principales: Bouquet, Lucie, Bôle-Richard, Elodie, Warda, Walid, Neto Da Rocha, Mathieu, Trad, Rim, Nicod, Clémentine, Haderbache, Rafik, Genin, Delphine, Ferrand, Christophe, Deschamps, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506905/
https://www.ncbi.nlm.nih.gov/pubmed/37173386
http://dx.doi.org/10.1038/s41434-023-00404-2