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RapaCaspase-9-based suicide gene applied to the safety of IL-1RAP CAR-T cells
Even if adoptive cell transfer (ACT) has already shown great clinical efficiency in different types of disease, such as cancer, some adverse events consistently occur, and suicide genes are an interesting system to manage these events. Our team developed a new medical drug candidate, a chimeric anti...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506905/ https://www.ncbi.nlm.nih.gov/pubmed/37173386 http://dx.doi.org/10.1038/s41434-023-00404-2 |