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Supraspinal neuroinflammation and anxio-depressive-like behaviors in young- and older- adult mice with osteoarthritis pain: the effect of morphine

RATIONALE: Asteoarthritis (OA) is a leading cause of chronic pain in the elderly population and is often associated with emotional comorbidities such as anxiety and depression. Despite age is a risk factor for both OA and mood disorders, preclinical studies are mainly conducted in young adult animal...

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Detalles Bibliográficos
Autores principales: Amodeo, Giada, Franchi, Silvia, D’Agnelli, Simona, Galimberti, Giulia, Baciarello, Marco, Bignami, Elena Giovanna, Sacerdote, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506934/
https://www.ncbi.nlm.nih.gov/pubmed/37530884
http://dx.doi.org/10.1007/s00213-023-06436-1