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Disentangling the roles of aneuploidy, chromosomal instability and tumour heterogeneity in developing resistance to cancer therapies

Aneuploidy is defined as the cellular state of having a number of chromosomes that deviates from a multiple of the normal haploid chromosome number of a given organism. Aneuploidy can be present in a static state: Down syndrome individuals stably maintain an extra copy of chromosome 21 in their cell...

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Detalles Bibliográficos
Autores principales: Andrade, Joana Reis, Gallagher, Annie Dinky, Maharaj, Jovanna, McClelland, Sarah Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506951/
https://www.ncbi.nlm.nih.gov/pubmed/37721639
http://dx.doi.org/10.1007/s10577-023-09737-5