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Disentangling the roles of aneuploidy, chromosomal instability and tumour heterogeneity in developing resistance to cancer therapies
Aneuploidy is defined as the cellular state of having a number of chromosomes that deviates from a multiple of the normal haploid chromosome number of a given organism. Aneuploidy can be present in a static state: Down syndrome individuals stably maintain an extra copy of chromosome 21 in their cell...
Autores principales: | Andrade, Joana Reis, Gallagher, Annie Dinky, Maharaj, Jovanna, McClelland, Sarah Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506951/ https://www.ncbi.nlm.nih.gov/pubmed/37721639 http://dx.doi.org/10.1007/s10577-023-09737-5 |
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