β(2)-AR inhibition enhances EGFR antibody efficacy hampering the oxidative stress response machinery

The β2-Adrenergic receptor (β2-ARs) is a cell membrane-spanning G protein-coupled receptors (GPCRs) physiologically involved in stress-related response. In many cancers, the β2-ARs signaling drives the tumor development and transformation, also promoting the resistance to the treatments. In HNSCC ce...

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Detalles Bibliográficos
Autores principales: Del Vecchio, Vitale, Mele, Luigi, Panda, Sameer Kumar, Sanchez-Pajares, Ibone Rubio, Mosca, Laura, Tirino, Virginia, Barbieri, Massimiliano, Bruzzese, Francesca, Luciano, Antonio, Marino, Federica Zito, Accardo, Marina, Nicoletti, Giovanni Francesco, Papaccio, Gianpaolo, Barbieri, Antonio, Desiderio, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507049/
https://www.ncbi.nlm.nih.gov/pubmed/37723219
http://dx.doi.org/10.1038/s41419-023-06129-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507049/
https://www.ncbi.nlm.nih.gov/pubmed/37723219
http://dx.doi.org/10.1038/s41419-023-06129-9

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