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Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis
Massive expansion of immature and suppressive myeloid cells is a common feature of malignant solid tumors. Over-expression of cyclin-dependent kinase 20, also known as cell cycle-related kinase (CCRK), in hepatocellular carcinoma (HCC) correlates with reduced patient survival and low immunotherapy r...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507137/ https://www.ncbi.nlm.nih.gov/pubmed/37731616 http://dx.doi.org/10.1016/j.isci.2023.107626 |