Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis

Massive expansion of immature and suppressive myeloid cells is a common feature of malignant solid tumors. Over-expression of cyclin-dependent kinase 20, also known as cell cycle-related kinase (CCRK), in hepatocellular carcinoma (HCC) correlates with reduced patient survival and low immunotherapy r...

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Detalles Bibliográficos
Autores principales: Zhou, Jingying, Wang, Huanyu, Shu, Ting, Wang, Jing, Yang, Weiqin, Li, Jingqing, Ding, Lipeng, Liu, Man, Sun, Hanyong, Wong, John, Lai, Paul Bo-san, Tsang, Shun-Wa, Ward, Simon E., Chow, King-Lau, Sung, Joseph Jao-yiu, Sze-Lok Cheng, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507137/
https://www.ncbi.nlm.nih.gov/pubmed/37731616
http://dx.doi.org/10.1016/j.isci.2023.107626

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