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Deficiency in AK9 causes asthenozoospermia and male infertility by destabilising sperm nucleotide homeostasis
BACKGROUND: Asthenozoospermia is the primary cause of male infertility; however, its genetic aetiology remains poorly understood. Adenylate kinase 9 (AK9) is highly expressed in the testes of humans and mice and encodes a type of adenosine kinase that is functionally involved in cellular nucleotide...
Autores principales: | Sha, Yanwei, Liu, Wensheng, Li, Shu, Osadchuk, Ludmila V., Chen, Yongjie, Nie, Hua, Gao, Shuai, Xie, Linna, Qin, Weibing, Zhou, Huiliang, Li, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507140/ https://www.ncbi.nlm.nih.gov/pubmed/37713809 http://dx.doi.org/10.1016/j.ebiom.2023.104798 |
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