Targeting glutamine metabolic reprogramming of SLC7A5 enhances the efficacy of anti-PD-1 in triple-negative breast cancer

BACKGROUND: Triple-negative breast cancer (TNBC) is a heterogeneous disease that is characterized by metabolic disruption. Metabolic reprogramming and tumor cell immune escape play indispensable roles in the tumorigenesis that leads to TNBC. METHODS: In this study, we constructed and validated two p...

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Detalles Bibliográficos
Autores principales: Huang, Renhong, Wang, Han, Hong, Jin, Wu, Jiayi, Huang, Ou, He, Jianrong, Chen, Weiguo, Li, Yafen, Chen, Xiaosong, Shen, Kunwei, Wang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507177/
https://www.ncbi.nlm.nih.gov/pubmed/37731509
http://dx.doi.org/10.3389/fimmu.2023.1251643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507177/
https://www.ncbi.nlm.nih.gov/pubmed/37731509
http://dx.doi.org/10.3389/fimmu.2023.1251643

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