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Obesity reduces hippocampal structure and function in older African Americans with the APOE-ε4 Alzheimer’s disease risk allele

INTRODUCTION: Excess body weight and Alzheimer’s disease (AD) disproportionately affect older African Americans. While mid-life obesity increases risk for AD, few data exist on the relationship between late-life obesity and AD, or how obesity-based and genetic risk for AD interact. Although the APOE...

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Detalles Bibliográficos
Autores principales: Osiecka, Zuzanna, Fausto, Bernadette A., Gills, Joshua L., Sinha, Neha, Malin, Steven K., Gluck, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507275/
https://www.ncbi.nlm.nih.gov/pubmed/37731955
http://dx.doi.org/10.3389/fnagi.2023.1239727