ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development

To determine the roles of endoplasmic reticulum (ER) stress and trained immunity, we performed transcriptome analyses on the thoracic aorta (TA) and abdominal aorta (AA) from the angiotensin II (Ang II)-HFD-ApoE-KO aneurysm model and made significant findings: 1) Ang II bypassed HFD-induced metaboli...

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Detalles Bibliográficos
Autores principales: Lu, Yifan, Sun, Yu, Saaoud, Fatma, Shao, Ying, Xu, Keman, Jiang, Xiaohua, Wu, Sheng, Yu, Jun, Snyder, Nathaniel W., Yang, Ling, Shi, Xinghua Mindy, Zhao, Huaqing, Wang, Hong, Yang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507336/
https://www.ncbi.nlm.nih.gov/pubmed/37731512
http://dx.doi.org/10.3389/fimmu.2023.1268916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507336/
https://www.ncbi.nlm.nih.gov/pubmed/37731512
http://dx.doi.org/10.3389/fimmu.2023.1268916

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