Cargando…

Accumulation of endogenous adenosine improves cardiomyocyte metabolism via epigenetic reprogramming in an ischemia-reperfusion model

Adenosine kinase (ADK) plays the major role in cardiac adenosine metabolism, so that inhibition of ADK increases myocardial adenosine levels. While the cardioprotective actions of extracellular adenosine against ischemia/reperfusion (I/R) are well-established, the role of cellular adenosine in prote...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Peng, Gao, Rifeng, Wu, Tingting, Zhang, Jinyan, Sun, Xiaolei, Fan, Fan, Wang, Cong, Qian, Sanli, Li, Bingyu, Zou, Yunzeng, Huo, Yuqing, Fassett, John, Chen, Yingjie, Ge, Junbo, Sun, Aijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507380/
https://www.ncbi.nlm.nih.gov/pubmed/37725888
http://dx.doi.org/10.1016/j.redox.2023.102884