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Discovering immunoreceptor coupling and organization motifs

The recently determined cryo-EM structures of the T cell antigen receptor (TCR) and B cell antigen receptor (BCR) show in molecular details the interactions of the ligand-binding part with the signaling subunits but they do not reveal the signaling mechanism of these antigen receptors. Without knowi...

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Detalles Bibliográficos
Autor principal: Reth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507400/
https://www.ncbi.nlm.nih.gov/pubmed/37731510
http://dx.doi.org/10.3389/fimmu.2023.1253412