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Efficacy of abatacept treatment in a patient with enteropathy carrying a variant of unsignificance in CTLA4 gene: A case report

BACKGROUND: Cytotoxic T Lymphocyte Antigen-4 (CTLA4) deficiency is a genetic defect that causes a common variable immunodeficiency (CVID) clinical phenotype. Several studies have reported an association between CTLA mutations or variants and various autoimmune diseases. Targeted therapy models, whic...

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Detalles Bibliográficos
Autores principales: Musabak, Ugur, Erdoğan, Tuba, Ceylaner, Serdar, Özbek, Emre, Suna, Nuretdin, Özdemir, Binnaz Handan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507547/
https://www.ncbi.nlm.nih.gov/pubmed/37731560
http://dx.doi.org/10.12998/wjcc.v11.i26.6176