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Topography of mutational signatures in human cancer

The somatic mutations found in a cancer genome are imprinted by different mutational processes. Each process exhibits a characteristic mutational signature, which can be affected by the genome architecture. However, the interplay between mutational signatures and topographical genomic features has n...

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Detalles Bibliográficos
Autores principales: Otlu, Burçak, Díaz-Gay, Marcos, Vermes, Ian, Bergstrom, Erik N., Zhivagui, Maria, Barnes, Mark, Alexandrov, Ludmil B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507738/
https://www.ncbi.nlm.nih.gov/pubmed/37540596
http://dx.doi.org/10.1016/j.celrep.2023.112930