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Topography of mutational signatures in human cancer
The somatic mutations found in a cancer genome are imprinted by different mutational processes. Each process exhibits a characteristic mutational signature, which can be affected by the genome architecture. However, the interplay between mutational signatures and topographical genomic features has n...
Autores principales: | Otlu, Burçak, Díaz-Gay, Marcos, Vermes, Ian, Bergstrom, Erik N., Zhivagui, Maria, Barnes, Mark, Alexandrov, Ludmil B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507738/ https://www.ncbi.nlm.nih.gov/pubmed/37540596 http://dx.doi.org/10.1016/j.celrep.2023.112930 |
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