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Alternate-day fat diet and exenatide modulate the brain leptin JAK2/STAT3/SOCS3 pathway in a fat diet-induced obesity and insulin resistance mouse model

INTRODUCTION: Obesity is one of the most burdensome health problems and is closely linked to leptin resistance. The study examined whether an alternate-day high-fat diet (ADF) and/or GLP-1 agonist (exenatide) modulate brain leptin resistance caused by a high-fat diet (HFD). MATERIAL AND METHODS: Six...

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Detalles Bibliográficos
Autores principales: Tawfik, Mona K., Badran, Dahlia I., Keshawy, Mohammed M., Makary, Samy, Abdo, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507768/
https://www.ncbi.nlm.nih.gov/pubmed/37732053
http://dx.doi.org/10.5114/aoms/158534