En route to local glioblastoma treatment with temozolomide doped hyaluronan fibres: formulation and in vitro cell studies

We report the preparation, characterisation and in vitro tests of hyaluronan fibres containing up to 50 w/w% of temozolomide for local glyoblastoma treatment. These fibres form a hydrogel upon contact with cerebrospinal fluid on the treatment spot.

Detalles Bibliográficos
Autores principales: Belhajová, Marie, Vícha, Aleš, Burgert, Ladislav, Brožková, Iveta, Michalíčková, Ludmila, Hrdina, Radim, Moravec, Tomáš, Netuka, David, Musil, Zdeněk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507811/
https://www.ncbi.nlm.nih.gov/pubmed/37731694
http://dx.doi.org/10.1039/d3md00261f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507811/
https://www.ncbi.nlm.nih.gov/pubmed/37731694
http://dx.doi.org/10.1039/d3md00261f

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