Evolving prion-like tau conformers differentially alter postsynaptic proteins in neurons inoculated with distinct isolates of Alzheimer’s disease tau

OBJECTIVES: Although accumulation of misfolded tau species has been shown to predict cognitive decline in patients with Alzheimer’s disease (AD) and other tauopathies but with the remarkable diversity of clinical manifestations, neuropathology profiles, and time courses of disease progression remain...

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Detalles Bibliográficos
Autores principales: Hromadkova, Lenka, Kim, Chae, Haldiman, Tracy, Peng, Lihua, Zhu, Xiongwei, Cohen, Mark, de Silva, Rohan, Safar, Jiri G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507869/
https://www.ncbi.nlm.nih.gov/pubmed/37723591
http://dx.doi.org/10.1186/s13578-023-01133-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507869/
https://www.ncbi.nlm.nih.gov/pubmed/37723591
http://dx.doi.org/10.1186/s13578-023-01133-0

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