ADP-ribosylation-resistant rifabutin analogs show improved bactericidal activity against drug-tolerant M. abscessus in caseum surrogate

Necrotic lesions and cavities filled with caseum are a hallmark of mycobacterial pulmonary disease. Bronchocavitary Mycobacterium abscessus disease is associated with poor treatment outcomes. In caseum surrogate, M. abscessus entered an extended stationary phase showing tolerance to killing by most...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Min, Ganapathy, Uday S., Lan, Tian, Osiecki, Paulina, Sarathy, Jansy P., Dartois, Véronique, Aldrich, Courtney C., Dick, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508146/
https://www.ncbi.nlm.nih.gov/pubmed/37493373
http://dx.doi.org/10.1128/aac.00381-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508146/
https://www.ncbi.nlm.nih.gov/pubmed/37493373
http://dx.doi.org/10.1128/aac.00381-23

Ejemplares similares