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Lung microenvironments harbor Mycobacterium tuberculosis phenotypes with distinct treatment responses

Tuberculosis lung lesions are complex and harbor heterogeneous microenvironments that influence antibiotic effectiveness. Major strides have been made recently in understanding drug pharmacokinetics in pulmonary lesions, but the bacterial phenotypes that arise under these conditions and their contri...

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Detalles Bibliográficos
Autores principales: Walter, Nicholas D., Ernest, Jackie P., Dide-Agossou, Christian, Bauman, Allison A., Ramey, Michelle E., Rossmassler, Karen, Massoudi, Lisa M., Pauly, Samantha, Al Mubarak, Reem, Voskuil, Martin I., Kaya, Firat, Sarathy, Jansy P., Zimmerman, Matthew D., Dartois, Véronique, Podell, Brendan K., Savic, Radojka M., Robertson, Gregory T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508168/
https://www.ncbi.nlm.nih.gov/pubmed/37565762
http://dx.doi.org/10.1128/aac.00284-23