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Skeletal muscle fibers produce B-cell stimulatory factors in chronic myositis

INTRODUCTION: We aimed to identify B-cell-mediated immunomechanisms in inclusion body myositis (IBM) and polymyositis (PM) as part of the complex pathophysiology. MATERIALS AND METHODS: Human primary myotube cultures were derived from orthopedic surgery. Diagnostic biopsy specimens from patients wit...

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Detalles Bibliográficos
Autores principales: Carstens, Per-Ole, Müllar, Luisa M., Wrede, Arne, Zechel, Sabrina, Wachowski, Martin M., Brandis, Almuth, Krause, Sabine, Zierz, Stephan, Schmidt, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508232/
https://www.ncbi.nlm.nih.gov/pubmed/37731487
http://dx.doi.org/10.3389/fimmu.2023.1177721