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Baseline Cytomegalovirus Viremia at Cryptococcal Meningitis Diagnosis Is Associated With Long-term Increased Incident TB Disease and Mortality in a Prospective Cohort of Ugandan Adults With HIV

BACKGROUND: Adults with HIV-associated cryptococcal meningitis have overlapping burdens of cytomegalovirus (CMV) and tuberculosis (TB) coinfections. CMV infection/reactivation is strongly associated with CMV-specific memory T-cell activation and upregulation of type 1 interferons, which may lead to...

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Detalles Bibliográficos
Autores principales: Ellis, Jayne, Bangdiwala, Ananta S, Skipper, Caleb P, Tugume, Lillian, Nsangi, Laura, Matovu, John, Pastick, Katelyn A, Ssebambulidde, Kenneth, Morawski, Bozena M, Musubire, Abdu K, Schleiss, Mark R, Moore, David A J, Jarvis, Joseph N, Boulware, David R, Meya, David B, Castelnuovo, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508356/
https://www.ncbi.nlm.nih.gov/pubmed/37732168
http://dx.doi.org/10.1093/ofid/ofad449