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lncRNA HOTAIR promotes ROS generation and NLRP3 inflammasome activation by inhibiting Nrf2 in diabetic retinopathy

BACKGROUND: Diabetic retinopathy (DR) is a microvascular complication associated with damage to the retina due to inflammation induced by high glucose. Activation of the NLRP3 inflammasome plays a critical role in DR and its prevention is beneficial to patients. However, the regulation of long non-c...

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Detalles Bibliográficos
Autores principales: You, Hui, Li, Hongyu, Gou, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508377/
https://www.ncbi.nlm.nih.gov/pubmed/37713847
http://dx.doi.org/10.1097/MD.0000000000035155