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Analysis of DUX4 Expression in Bone Marrow and Re-Discussion of DUX4 Function in the Health and Disease

Objective: DUX4 is an embryonic transcription factor (TF) later silenced in somatic tissues, while active in germline testis cells. Re-expression in somatic cells has been revealed to be present in pathologic conditions such as dystrophy, leukemia, and other cancer types. Embryonic cells, cancer cel...

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Detalles Bibliográficos
Autores principales: Hangul, Ceren, Tokta, Oznur, Berker Karauzum, Sibel, Akkaya, Bahar, Yıldırım, Hulya, Tayfun Kupesiz, Funda, Akınel, Ayse Nur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of Turkish Pathology Societies 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508413/
https://www.ncbi.nlm.nih.gov/pubmed/34854471
http://dx.doi.org/10.5146/tjpath.2021.01564