Development of a multiscale mechanistic modeling framework integrating differential cellular kinetics of CAR T‐cell subsets and immunophenotypes in cancer patients

Chimeric antigen receptor (CAR) T‐cell subsets and immunophenotypic composition of the pre‐infusion product, as well as their longitudinal changes following infusion, are expected to affect CAR T‐cell expansion, persistence, and clinical outcomes. Herein, we sequentially evolved our previously descr...

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Detalles Bibliográficos
Autores principales: Salem, Ahmed M., Mugundu, Ganesh M., Singh, Aman P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508581/
https://www.ncbi.nlm.nih.gov/pubmed/37448297
http://dx.doi.org/10.1002/psp4.13009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508581/
https://www.ncbi.nlm.nih.gov/pubmed/37448297
http://dx.doi.org/10.1002/psp4.13009

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