Iron-overload-induced ferroptosis in mouse cerebral toxoplasmosis promotes brain injury and could be inhibited by Deferiprone

Iron is a trace metal element that is essential for the survival of cells and parasites. The role of iron in cerebral toxoplasmosis (CT) is still unclear. Deferiprone (DFP) is the orally active iron chelator that binds iron in a molar ratio of 3:1 (ligand:iron) and promotes urinary iron excretion to...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Chong, Xie, Linding, Xing, Yien, Liu, Min, Yang, Jun, Gao, Nannan, Cai, Yihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508604/
https://www.ncbi.nlm.nih.gov/pubmed/37651502
http://dx.doi.org/10.1371/journal.pntd.0011607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508604/
https://www.ncbi.nlm.nih.gov/pubmed/37651502
http://dx.doi.org/10.1371/journal.pntd.0011607

Ejemplares similares