Development of a novel in vitro model to study the modulatory role of the respiratory complex I in macrophage effector functions

Increasing evidence demonstrate that the electron transfer chain plays a critical role in controlling the effector functions of macrophages. In this work, we have generated a Ndufs4−/− murine macrophage cell lines. The Ndufs4 gene, which encodes a supernumerary subunit of complex I, is a mutational...

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Detalles Bibliográficos
Autores principales: Serrano-Lorenzo, Pablo, Gobelli, Dino, Garrido-Moraga, Rocío, Esteban-Amo, María J., López-López, José R., Orduña, Antonio, de la Fuente, Miguel A., Martín, Miguel A., Simarro, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508620/
https://www.ncbi.nlm.nih.gov/pubmed/37725617
http://dx.doi.org/10.1371/journal.pone.0291442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508620/
https://www.ncbi.nlm.nih.gov/pubmed/37725617
http://dx.doi.org/10.1371/journal.pone.0291442

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