The Drosophila homolog of APP promotes Dscam expression to drive axon terminal growth, revealing interaction between Down syndrome genes

Down syndrome (DS) is caused by triplication of human chromosome 21 (HSA21). Although several HSA21 genes have been found to be responsible for aspects of DS, whether and how HSA21 genes interact with each other is poorly understood. DS patients and animal models present with a number of neurologica...

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Detalles Bibliográficos
Autores principales: Pizzano, Sarah, Sterne, Gabriella R., Veling, Macy W., Xu, L. Amanda, Hergenreder, Ty, Ye, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508694/
https://www.ncbi.nlm.nih.gov/pubmed/37712356
http://dx.doi.org/10.1242/dmm.049725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508694/
https://www.ncbi.nlm.nih.gov/pubmed/37712356
http://dx.doi.org/10.1242/dmm.049725

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