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The Drosophila homolog of APP promotes Dscam expression to drive axon terminal growth, revealing interaction between Down syndrome genes
Down syndrome (DS) is caused by triplication of human chromosome 21 (HSA21). Although several HSA21 genes have been found to be responsible for aspects of DS, whether and how HSA21 genes interact with each other is poorly understood. DS patients and animal models present with a number of neurologica...
Autores principales: | Pizzano, Sarah, Sterne, Gabriella R., Veling, Macy W., Xu, L. Amanda, Hergenreder, Ty, Ye, Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508694/ https://www.ncbi.nlm.nih.gov/pubmed/37712356 http://dx.doi.org/10.1242/dmm.049725 |
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