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Leucine-rich repeat kinase 2 at a glance

Leucine-rich repeat kinase 2 (LRRK2) is a multidomain scaffolding protein with dual guanosine triphosphatase (GTPase) and kinase enzymatic activities, providing this protein with the capacity to regulate a multitude of signalling pathways and act as a key mediator of diverse cellular processes. Much...

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Detalles Bibliográficos
Autores principales: Zhu, Christiane, Herbst, Susanne, Lewis, Patrick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508695/
https://www.ncbi.nlm.nih.gov/pubmed/37698513
http://dx.doi.org/10.1242/jcs.259724