Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis

Mitochondrial DNA (mtDNA) mutations are frequently observed in cancer, but their contribution to tumor progression is controversial. To evaluate the impact of mtDNA variants on tumor growth and metastasis, we created human melanoma cytoplasmic hybrid (cybrid) cell lines transplanted with wildtype mt...

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Detalles Bibliográficos
Autores principales: Shelton, Spencer D., House, Sara, Ramesh, Vijayashree, Chen, Zhenkang, Wei, Tao, Wang, Xun, Llamas, Claire B., Venigalla, Siva Sai Krishna, Menezes, Cameron J., Zhao, Zhiyu, Gill, Jennifer G., DeBerardinis, Ralph J., Morrison, Sean J., Tasdogan, Alpaslan, Mishra, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508716/
https://www.ncbi.nlm.nih.gov/pubmed/37732192
http://dx.doi.org/10.1101/2023.09.01.555986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508716/
https://www.ncbi.nlm.nih.gov/pubmed/37732192
http://dx.doi.org/10.1101/2023.09.01.555986

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