Diverse mutant selection windows shape spatial heterogeneity in evolving populations

Mutant selection windows (MSWs), the range of drug concentrations that select for drug-resistant mutants, have long been used as a model for predicting drug resistance and designing optimal dosing strategies in infectious disease. The canonical MSW model offers comparisons between two subtypes at a...

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Detalles Bibliográficos
Autores principales: King, Eshan S., Pierce, Beck, Hinczewski, Michael, Scott, Jacob G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508720/
https://www.ncbi.nlm.nih.gov/pubmed/37732215
http://dx.doi.org/10.1101/2023.03.09.531899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508720/
https://www.ncbi.nlm.nih.gov/pubmed/37732215
http://dx.doi.org/10.1101/2023.03.09.531899

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