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Understanding the heterogeneity of alloreactive natural killer cell function in kidney transplantation

Human Natural Killer (NK) cells are heterogeneous lymphocytes regulated by variegated arrays of germline-encoded activating and inhibitory receptors. They acquire the ability to detect polymorphic self-antigen via NKG2A/HLA-E or KIR/HLA-I ligand interactions through an education process. Correlation...

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Detalles Bibliográficos
Autores principales: Ruan, Dan Fu, Fribourg, Miguel, Yuki, Yuko, Park, Yeon-Hwa, Martin, Maureen, Kelly, Geoffrey, Lee, Brian, Miguel de Real, Ronaldo, Lee, Rachel, Geanon, Daniel, Kim-Schulze, Seunghee, McCarthy, Melissa, Chun, Nicholas, Cravedi, Paolo, Carrington, Mary, Heeger, Peter S., Horowitz, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508724/
https://www.ncbi.nlm.nih.gov/pubmed/37732256
http://dx.doi.org/10.1101/2023.09.01.555962