STAT3 is a genetic modifier of TGF-beta induced EMT in KRAS mutant pancreatic cancer

Oncogenic mutations in KRAS are among the most common in cancer. Classical models suggest that loss of epithelial characteristics and the acquisition of mesenchymal traits are associated with cancer aggressiveness and therapy resistance. However, the mechanistic link between these phenotypes and mut...

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Detalles Bibliográficos
Autores principales: D’Amico, Stephen, Kirillov, Varvara, Petrenko, Oleksi, Reich, Nancy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508731/
https://www.ncbi.nlm.nih.gov/pubmed/37732258
http://dx.doi.org/10.1101/2023.09.01.555946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508731/
https://www.ncbi.nlm.nih.gov/pubmed/37732258
http://dx.doi.org/10.1101/2023.09.01.555946

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