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Host cell glycosylation selects for infection with CCR5- versus CXCR4-tropic HIV-1
HIV-1 infection involves a selection bottleneck that leads to transmission of one or a few HIV variants, which nearly always use CCR5 as the coreceptor (R5 viruses) for viral entry as opposed to CXCR4 (X4 viruses). The host properties that drive this selection are not well understood and may hold ke...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508750/ https://www.ncbi.nlm.nih.gov/pubmed/37732222 http://dx.doi.org/10.1101/2023.09.05.556399 |