Drugs of abuse hijack a mesolimbic pathway that processes homeostatic need

Addiction prioritizes drug use over innate needs by “hijacking” brain circuits that direct motivation, but how this develops remains unclear. Using whole-brain FOS mapping and in vivo single-neuron calcium imaging, we find that drugs of abuse augment ensemble activity in the nucleus accumbens (NAc)...

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Detalles Bibliográficos
Autores principales: Tan, Bowen, Browne, Caleb J., Nöbauer, Tobias, Vaziri, Alipasha, Friedman, Jeffrey M., Nestler, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508763/
https://www.ncbi.nlm.nih.gov/pubmed/37732251
http://dx.doi.org/10.1101/2023.09.03.556059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508763/
https://www.ncbi.nlm.nih.gov/pubmed/37732251
http://dx.doi.org/10.1101/2023.09.03.556059

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