UBC13-mediated template switching promotes replication stress resistance in FBH1-deficient cells

The proper resolution of DNA damage during replication is essential for genome stability. FBH1, a UvrD, helicase plays crucial roles in the DNA damage response. FBH1 promotes double strand break formation and signaling in response to prolonged replication stress to initiate apoptosis. Human FBH1 reg...

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Detalles Bibliográficos
Autores principales: Hawks, Alexandra L., Bergmann, Amy, McCraw, Tyler J., Mason, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508767/
https://www.ncbi.nlm.nih.gov/pubmed/37732269
http://dx.doi.org/10.1101/2023.09.04.556280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508767/
https://www.ncbi.nlm.nih.gov/pubmed/37732269
http://dx.doi.org/10.1101/2023.09.04.556280

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