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Long-term longitudinal analysis of 4,187 participants reveals new insights into determinants of incident clonal hematopoiesis

Clonal hematopoiesis (CH), characterized by blood cells predominantly originating from a single mutated hematopoietic stem cell, is linked to diverse aging-related diseases, including hematologic malignancy and atherosclerotic cardiovascular disease (ASCVD). While CH is common among older adults, th...

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Detalles Bibliográficos
Autores principales: Uddin, Md Mesbah, Saadatagah, Seyedmohammad, Niroula, Abhishek, Yu, Bing, Hornsby, Whitney, Ganesh, Shriienidhie, Lannery, Kim, Shuermans, Art, Honigberg, Michael C., Bick, Alexander G., Libby, Peter, Ebert, Benjamin L., Ballantyne, Christie M., Natarajan, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508802/
https://www.ncbi.nlm.nih.gov/pubmed/37732181
http://dx.doi.org/10.1101/2023.09.05.23295093