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Obesity Prediction in Young Adults from the Jerusalem Perinatal Study: Contribution of Polygenic Risk and Early Life Exposures

We assessed whether adding early life exposures to a model based on polygenic risk score (PRS) improves prediction of obesity risk. We used a birth cohort with data at birth and BMI and waist circumference (WC) measured at age 32. The PRS was composed of SNPs identified in GWAS for BMI. Linear and l...

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Detalles Bibliográficos
Autores principales: Hochner, Hagit, Butterman, Rachely, Margaliot, Ido, Friedlander, Yechiel, Linial, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508819/
https://www.ncbi.nlm.nih.gov/pubmed/37732179
http://dx.doi.org/10.1101/2023.09.05.23295076