Selective loss of CD107a TIGIT+ memory HIV-1-specific CD8+ T cells in PLWH over a decade of ART

The co-expression of inhibitory receptors (IRs) is a hallmark of CD8+ T-cell exhaustion (Tex) in people living with HIV-1 (PLWH). Understanding alterations of IRs expression in PLWH on long-term antiretroviral treatment (ART) remains elusive but is critical to overcoming CD8+ Tex and designing novel...

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Detalles Bibliográficos
Autores principales: Blanch-Lombarte, Oscar, Ouchi, Dan, Jimenez-Moyano, Esther, Carabelli, Julieta, Marin, Miguel Angel, Peña, Ruth, Pelletier, Adam, Talla, Aarthi, Sharma, Ashish, Dalmau, Judith, Santos, José Ramón, Sékaly, Rafick-Pierre, Clotet, Bonaventura, Prado, Julia G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508883/
https://www.ncbi.nlm.nih.gov/pubmed/37723971
http://dx.doi.org/10.7554/eLife.83737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508883/
https://www.ncbi.nlm.nih.gov/pubmed/37723971
http://dx.doi.org/10.7554/eLife.83737

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