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Ebselen, Iron Uptake Inhibitor, Alleviates Iron Overload-Induced Senescence-Like Neuronal Cells SH-SY5Y via Suppressing the mTORC1 Signaling Pathway

Increasing evidence highlights that excessive iron accumulation in the brain plays a vital role in neuronal senescence and is implicated in the pathogenesis of age-related neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD). Therefore, the chemical c...

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Detalles Bibliográficos
Autores principales: Mukem, Sirirak, Sayoh, Ibrahim, Maungchanburi, Saowanee, Thongbuakaew, Tipsuda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509000/
https://www.ncbi.nlm.nih.gov/pubmed/37731679
http://dx.doi.org/10.1155/2023/6641347