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Cortical Lewy body injections induce long-distance pathogenic alterations in the non-human primate brain

Aggregation of α-synuclein (α-syn) is the cornerstone of neurodegenerative diseases termed synucleinopathies, which include Parkinson’s Disease (PD), Dementia with Lewy Bodies (DLB), and Multiple System Atrophy (MSA). These synucleinopathies are characterized by the deposit of aggregated α-syn in in...

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Detalles Bibliográficos
Autores principales: Teil, Margaux, Dovero, Sandra, Bourdenx, Mathieu, Arotcarena, Marie-Laure, Darricau, Morgane, Porras, Gregory, Thiolat, Marie-Laure, Trigo-Damas, Inés, Perier, Celine, Estrada, Cristina, Garcia-Carrillo, Nuria, Herrero, María Trinidad, Vila, Miquel, Obeso, José A., Bezard, Erwan, Dehay, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509171/
https://www.ncbi.nlm.nih.gov/pubmed/37726343
http://dx.doi.org/10.1038/s41531-023-00579-w