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Epithelial plasticity and innate immune activation promote lung tissue remodeling following respiratory viral infection

Epithelial plasticity has been suggested in lungs of mice following genetic depletion of stem cells but is of unknown physiological relevance. Viral infection and chronic lung disease share similar pathological features of stem cell loss in alveoli, basal cell (BC) hyperplasia in small airways, and...

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Detalles Bibliográficos
Autores principales: Beppu, Andrew K., Zhao, Juanjuan, Yao, Changfu, Carraro, Gianni, Israely, Edo, Coelho, Anna Lucia, Drake, Katherine, Hogaboam, Cory M., Parks, William C., Kolls, Jay K., Stripp, Barry R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509177/
https://www.ncbi.nlm.nih.gov/pubmed/37726288
http://dx.doi.org/10.1038/s41467-023-41387-3