A mechanism that ensures non-selective cytoplasm degradation by autophagy

In autophagy, a membrane cisterna called the isolation membrane expands, bends, becomes spherical, and closes to sequester cytoplasmic constituents into the resulting double-membrane vesicle autophagosome for lysosomal/vacuolar degradation. Here, we discover a mechanism that allows the isolation mem...

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Detalles Bibliográficos
Autores principales: Kotani, Tetsuya, Sakai, Yuji, Kirisako, Hiromi, Kakuta, Chika, Kakuta, Soichiro, Ohsumi, Yoshinori, Nakatogawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509180/
https://www.ncbi.nlm.nih.gov/pubmed/37726301
http://dx.doi.org/10.1038/s41467-023-41525-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509180/
https://www.ncbi.nlm.nih.gov/pubmed/37726301
http://dx.doi.org/10.1038/s41467-023-41525-x

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