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A mechanism that ensures non-selective cytoplasm degradation by autophagy
In autophagy, a membrane cisterna called the isolation membrane expands, bends, becomes spherical, and closes to sequester cytoplasmic constituents into the resulting double-membrane vesicle autophagosome for lysosomal/vacuolar degradation. Here, we discover a mechanism that allows the isolation mem...
Autores principales: | Kotani, Tetsuya, Sakai, Yuji, Kirisako, Hiromi, Kakuta, Chika, Kakuta, Soichiro, Ohsumi, Yoshinori, Nakatogawa, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509180/ https://www.ncbi.nlm.nih.gov/pubmed/37726301 http://dx.doi.org/10.1038/s41467-023-41525-x |
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