Inhibition of cGAS–STING pathway alleviates neuroinflammation-induced retinal ganglion cell death after ischemia/reperfusion injury

Acute glaucoma is a vision-threatening disease characterized by a sudden elevation in intraocular pressure (IOP), followed by retinal ganglion cell (RGC) death. Cytosolic double-stranded DNA (dsDNA)—a damage-associated molecular pattern (DAMP) that triggers inflammation and immune responses—has been...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Xingdi, Yu, Naiji, Ye, Zifan, Gu, Yuxiang, Zhang, Chengshou, Chen, Min, Wang, Kaijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509212/
https://www.ncbi.nlm.nih.gov/pubmed/37726272
http://dx.doi.org/10.1038/s41419-023-06140-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509212/
https://www.ncbi.nlm.nih.gov/pubmed/37726272
http://dx.doi.org/10.1038/s41419-023-06140-0

Ejemplares similares